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Scientific studies of Darvocet-N (propoxyphene napsylate and acetaminophen) did not involve ample figures of topics aged 65 and around to determine whether they react in a different way from young topics. Having said that, postmarketing reviews suggest that sufferers around the age of sixty five might be far more at risk of CNS-similar Unwanted effects.
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Individuals need to be encouraged to report pain and adverse experiences occurring through therapy. Individualization of dosage is critical to help make optimal use of the medication.
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The affected website individual could possibly be detoxified by gradual reduction from the dose. Gastrointestinal disturbances or dehydration ought to be addressed with supportive care.
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No formal pharmacokinetic study of possibly propoxyphene by itself or in combination with acetaminophen has become carried out in sufferers with mild, average or critical hepatic impairment.